WarfarinPPIs can occasionally enhance the effects of warfarin. The warfarin if omeprazole, pantoprazole, or esomeprazole is started or stopped.
by A Çelebi 2024 Cited by 2macokinetics and pharmacodynamics of warfarin. (6). Because omeprazole increases the r-warfarin blood lev- els and reduces thrombosis by 10%, omeprazole should.
Omeprazole and Warfarin Warfarin is an anti-clotting drug (or anticoagulant) used to lower the risk of blood clots. Taking omeprazole in combination with warfarin may jeopardize blood coagulation and lead to abnormal bleeding and even death.
The Summary of Product Characteristics (SPC) for warfarin lists omeprazole as a medication that can enhance the anticoagulant effect of warfarin
Blood thinners, such as Jantoven (warfarin): Omeprazole can increase the effects of warfarin, raising the risk of bleeding. Antidepressants
Interactions Blood thinners, such as Jantoven (warfarin): Omeprazole can increase the effects of warfarin, raising the risk of bleeding.
by Q Zhou 2024 Cited by 15Abstract: Clinically observed warfarin-omeprazole interaction has been found to be associated with the inhibition of R- warfarin hydroxylation by omeprazole
Which drugs interact with omeprazole? Warfarin: Abnormal bleeding could result from mixing omeprazole and warfarin, a medication that prevents
by Q Zhou 2024 Cited by 15Abstract: Clinically observed warfarin-omeprazole interaction has been found to be associated with the inhibition of R- warfarin hydroxylation by omeprazole
Hence Omeprazole being a much more expensive drug than it is now.....