Treatments for MH and Heat Stroke The treatment for anesthesia-induced MH is a drug called dantrolene. For heat stroke, options are limited to
Dantrolene is a direct-acting skeletal muscle relaxant used for the treatment of Nelson TE: Dantrolene dose response in malignant hyperthermia-susceptible (MHS
time before the. administration of dantrolene, the CGS was higher. MH episode complications. Serious complications or death associated with the MH.
prevention of MH is the same as for adults for these indications [see Dosage and Administration dantrolene after administration of a single RYANODEX dose of
Dantrolene is the only clinically available specific treatment for MH and, after discontinuation of triggering agents, should always be the initial treatment for any suspected MH episode. The recommended initial dose of dantrolene is 2.5 mg/kg bolus with repeated boluses as needed until hypermetabolism is controlled.
To treat an MH episode, an initial dose of dantrolene at 2.5 mg/kg is recommended, with a suggested upper limit of 10 mg/kg.
To treat an MH episode, an initial dose of dantrolene at 2.5 mg/kg is recommended, with a suggested upper limit of 10 mg/kg.
by B Carlson Cited by 1IV dantrolene is the only drug FDA-approved for the treatment of MH. Dantrolene is a hydantoin-derivative skeletal muscle relaxant that acts by
Our study of 229 MH episodes with documented dantrolene doses found a wide range with an initial median dantrolene dose of 2.4 mg/kg and a total
Comments
MH
MH