by JW Romito 2024 Cited by 99PO: 1–4 h, The anticholinergic effects of cyproheptadine can be additive with other anticholinergics. baclofen pump despite oral baclofen
anticholinergic delirium. Case reports also describe its use in the reversal of respiratory depression caused by baclofen overdose. baclofen therapy.
Baclofen Baclofen is another muscle relaxant that works in the spinal cord These Anticholinergic and dopaminergic medicines block cholinergic nerve
For example, baclofen is moderately anticholinergic on the Anticholinergic Risk Scale (Rudolph et al, 2024) but is not on Chew's scale (Chew et al, 2024).
Trazodone and baclofen only have a mild effect on the anticholinergic system. The risk of anticholinergic syndrome with this medication is rather low.
However, I recently noticed that baclofen is listed on some anticholinergic drug charts as having moderate/high anticholinergic activity. Given Phenibut's close structural resemblance to Baclofen, I'm curious if anyone more knowledgeable than myself can comment on Phenibut's potential anticholinergic activity.
Higher anticholinergic adults due to anticholinergic effects (especially cyclobenzaprine), risk of sedation, and risk of fractures baclofen, tizanidine.
However, I recently noticed that baclofen is listed on some anticholinergic drug charts as having moderate/high anticholinergic activity. Given Phenibut's close structural resemblance to Baclofen, I'm curious if anyone more knowledgeable than myself can comment on Phenibut's potential anticholinergic activity.
anticholinergic agents-anticholinergic syndrome. Historically Baclofen Cardiovascular medications - Captopril - Digoxin - Diltiazem
As for everyone else ... life keeps adding on the 'happy' {sarcasm}.
My neurologist decided to prescribe a more powerful tool to manage the pain in my feet. So, he gave me a foot cream. What wasn't obvious was the non-prescribed 'side effects' of the foot cream which included ... (sigh) ...
Well, as my feet have been hurting like sons-a-bitches, I was slathering that cream on three and four times a day. It had minimal positive effect which was leagues ahead of the pain I was going through. Besides, it was foot cream. What was the worse that could happen?
Baclofen (2%) ~ [Lightheadedness or fainting, trouble seeing, severe tiredness, weakness],
Cyclobenzaprine (2%) ~ [Anxiety, restlessness, seeing or hearing things that are not there, severe drowsiness, fainting, or confusion],
Diclofenac (3%) ~ [Sudden or severe headache, or problems with vision, speech, or walking],
Gabapentin (6%) ~ [Behavior problems, aggression, restlessness, trouble concentrating, moodiness (especially in children), problems with coordination, shakiness, unsteadiness, unusual moods, or behaviors, thoughts of hurting yourself, feeling depressed, dizziness, drowsiness, sleepiness, tiredness],
Lidocaine (2%) ~ [which, somewhat stunningly, isn't trying to fuck with my head]
So I've been staggering around in a semi-lucid state for the past several days, unable to figure out why I couldn't do much, if any, writing. It took me complaining to my wife to provide some clarity.
I repeat - it is freaking foot cream!
I've stopped with the foot-crack and am back to dealing with the pain. Hopefully I'll be back to writing soon too.
James aka FinalStand