Obinutuzumab vs rituximab 📣 @obinutuzumab_vs_ritu

About the channel @obinutuzumab_vs_ritu

Obinutuzumab vs rituximab — Rituximab, the first anti-CD20 monoclonal antibody, has dramatically improved outcomes for patients with B-cell lymphoproliferative disorders. Obinutuzumab was developed to potentiate activity and overcome resistance to rituximab. Clinical data suggest that obinutuzumab is superior to rituximab in f Rituximab, the first anti-CD20 monoclonal antibody, has dramatically improved outcomes for patients with B-cell lymphoproliferative disorders. Obinutuzumab was developed to potentiate activity and overcome resistance to rituximab. Clinical data suggest that obinutuzumab is superior to rituximab in f

Comments

User8634

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User2485

... typos and naive errors with homonyms:
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User3585

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A lot of different possibilities!

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To compare the safety of obinutuzumab by: 5. Comparing how well obinutuzumab versus rituximab in treating the disease. 6. Comparing the

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by T Berger 2024Introduction - The recent GALLIUM study showed an advantage of 7% in progression free survival in favor of obinutuzumab (G) vs. rituximab

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Obinutuzumab is a glycoengineered type II anti-CD20 monoclonal antibody (mAb), recognizing a unique CD20 extracellular membrane epitope with enhanced antibody dependent cellular cytotoxicity (ADCC) vs rituximab. We hypothesize that obinutuzumab vs rituximab will significantly enhance in-vitro and in-vivo cytotoxicity against PMBL.

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Our analysis shows that O-chemo was more costly ( 40,477 for obinutuzumab vs 25,503 for rituximab) but more effective, with expected OS prolongation of 0.97 years (14.31 LYs for obinutuzumab vs 13.35 for rituximab). This corresponds to a 0.88 QALY gain (12.55 QALYs for obinutuzumab vs 11.68 QALYs for rituximab).

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Obinutuzumab in combination with bendamustine for treating rituximab rituximab, often followed by maintenance therapy with rituximab. However

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Obinutuzumab vs. rituximab in follicular lymphoma explained in Quick Take video:

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Obinutuzumab vs. rituximab in follicular lymphoma explained in Quick Take video:

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Obinutuzumab vs rituximab