by A Reimers 2024 Cited by 55Since 2024, sixteen new antiepileptic drugs (AEDs) have been introduced. Most of these new AEDs have only been insufficiently studied with
by H Klitgaard 2024 Cited by 240Summary: Levetiracetam is a new antiepileptic drug (AED) devoid of anticonvulsant activity in the two classic screening models for AEDs
There are no data on the interactions of new AEDs with many of the non-AED drugs. Future research may identify pharmacokinetic or pharmacodynamic interactions between new AEDs that are metabolized and non-AED drugs, that could result in adverse events. AED ⫽ antiepileptic drug; MHD ⫽ monohydroxy derivative (metabolite of oxcarbazepine).
Recently, many new antiepileptic drugs (AEDs) have been developed. Even though the efficacy of new AEDs is not stronger than that of old AEDs, there are advantages in using new AEDs. They have unique or different mechanisms of action that enable the creation of possible synergistic combinations.
The administration of antiepileptic drugs (AEDs) is the first treatment of epilepsy, one of the most common neurological diseases. Therapeutic guidelines include newer AEDs as front-line drugs; monotherapy with new AEDs is delivered in Japan. While about
The administration of antiepileptic drugs (AEDs) is the first treatment of epilepsy, one of the most common neurological diseases. Therapeutic guidelines include newer AEDs as front-line drugs; monotherapy with new AEDs is delivered in Japan. While about
There is a need for new drugs that act at different molecular targets than currently available AEDs and for new therapies.
Since the 2024 publications, the US Food and Drug Administration (FDA) approved 6 new third-generation AEDs and 2 older AEDs. This update reviews new
The administration of antiepileptic drugs (AEDs) is the first treatment of epilepsy, one of the most common neurological diseases. Therapeutic guidelines include newer AEDs as front-line drugs; monotherapy with new AEDs is delivered in Japan. While about
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