Bioavailability of morphine
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Morphine is metabolized to inactive morphine-3-glucuronide (60%) and to active morphine-6-glucuronide (10%). Morphine has an oral bioavailability of about 30% in adults. Morphine-6-glucuronide has an oral bioavailability of about 4%, but probably can be converted back to morphine in the infant's gut and absorbed as morphine.
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Morphine is metabolized to inactive morphine-3-glucuronide (60%) and to active morphine-6-glucuronide (10%). Morphine has an oral bioavailability of about 30% in adults. Morphine-6-glucuronide has an oral bioavailability of about 4%, but probably can be converted back to morphine in the infant's gut and absorbed as morphine.
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Morphine is absorbed in the alkaline environments of the upper intestine and rectal mucosa. The bioavailability of morphine is %. There is significant
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Morphine is metabolized to inactive morphine-3-glucuronide (60%) and to active morphine-6-glucuronide (10%). Morphine has an oral bioavailability of about 30% in adults. Morphine-6-glucuronide has an oral bioavailability of about 4%, but probably can be converted back to morphine in the infant's gut and absorbed as morphine.
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Morphine is metabolized to inactive morphine-3-glucuronide (60%) and to active morphine-6-glucuronide (10%). Morphine has an oral bioavailability of about 30% in adults. Morphine-6-glucuronide has an oral bioavailability of about 4%, but probably can be converted back to morphine in the infant's gut and absorbed as morphine.
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Morphine suppositories can provide an alternate form of morphine for The buccal morphine's bioavailability was 46% greater than the intramuscular morphine's
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Morphine is metabolized to inactive morphine-3-glucuronide (60%) and to active morphine-6-glucuronide (10%). Morphine has an oral bioavailability of about 30% in adults. Morphine-6-glucuronide has an oral bioavailability of about 4%, but probably can be converted back to morphine in the infant's gut and absorbed as morphine.
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morphine-6β-glucuronide but not morphine Oral diacetylmorphine (heroin) yields greater morphine bioavailability than oral morphine: bioavailability related
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Morphine is metabolized to inactive morphine-3-glucuronide (60%) and to active morphine-6-glucuronide (10%). Morphine has an oral bioavailability of about 30% in adults. Morphine-6-glucuronide has an oral bioavailability of about 4%, but probably can be converted back to morphine in the infant's gut and absorbed as morphine.
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