Drugs: The use of immuno-suppressant drugs may lead to high uric acid in the body. uric acid levels in the body from increasing further.
However, the rats responded well to uricosuric drugs and diuretics. Probenecid and uricosuric diuretics such as tienilic acid induced hyperuricosuria due to the increase of fractional excretion of uric acid and/or the increase of the filtered amount of uric acid with the rise of plasma uric acid.
increase urinary excretion of uric acid used as second-line drugs in patients who are under-excretors of uric acid and in those resistant to or
Pyrazinamide and Ethambutol are antitubercular drugs that raise Uric acid levels by lowering excretion and increasing uric acid reabsorption and cause
Drugs raise serum uric acid level by increasing uric acid reabsorption and/or decreasing uric acid secretion in gout. Adequate hydration and routine uric acid level monitoring should be encouraged for drugs known to induce hyperuricaemia.
Allopurinol is the mainstay of drug therapy in patients with hyperuricemia who develop uric acid stones. increase the solubility of uric acid.
Drugs raise serum uric acid level by an increase of uric acid reabsorption and/or decrease in uric acid secretion. Several drugs may also increase uric acid production. In this review, drugs leading to hyperuricaemia are summarized with regard to their mechanism of action and clinical significance.
Uricosuric agents lower uric acid levels by inhibiting renal tubular reabsorption of uric acid, thereby increasing net renal excretion of uric acid. These
The PharmGKB Uric Acid-Lowering Drugs Pathway, PD covers drugs that either inhibit formation of uric acid or act directly upon uric acid to increase secretion.
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