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Thyroxine (levothyroxine sodium) (T 4 ) is the hormone of choice for thyroid hormone replacement owing to its consistent potency and its duration of action.
Levothyroxine is deiodinated in peripheral tissues to form Tri-iodothyronine which is thought to be the active tissue form of thyroid hormone. Pharmacodynamic effects. Tri-iodothyronine is certainly more rapid acting and has a shorter duration of action than Levothyroxine. The chief action of Levothyroxine is to increase the rate of cell metabolism
Liothyronine is considered to present more potent and faster actions compared to Levothyroxine, but the duration is comparatively shorter. The
It also has a long duration of action occurring between 1 to 3 weeks, even following the discontinuance of the drug. Distribution. Levothyroxine
Includes Levothyroxine indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse
The biological action of liothyronine sodium is similar to levothyroxine sodium, but it has a quicker onset and shorter duration of action (effects develop in a
Onset. More rapid onset of action than levothyroxine. Following a single IV dose, metabolic response is detectable within 2 4 hours and peak therapeutic effects occur within 2 days. Duration. Shorter duration of action than levothyroxine. Distribution Extent
It also has a long duration of action occurring between 1 to 3 weeks, even following the discontinuance of the drug. Distribution. Levothyroxine
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