Acyclovir nephrotoxicity

☑️@acyclovir_nephrotoxi · 3522 subscribers · Content 18+ 🔞
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Actual: Although nephrotoxicity due to intravenous infusion of valacyclovir and/or acyclovir is not uncommon, oral valacyclovir therapy is rarely associated with nephrotoxicity in patients with no history of renal insufficiency. Additionally, concurrent nephrotoxicity and neurotoxicity due to valacyclovir and/or acyclovir are rarely reported.
4.6 rating 2025-04-26
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Enter a drug name to check for any interactions. amikacin. No Results acyclovir. acyclovir and amikacin both increase nephrotoxicity and/or

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Dosing Uses. AdultPediatric. ADULT. Dosage Forms Strengths. injectable acyclovir. acyclovir and amikacin both increase nephrotoxicity and/or

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Li, Evaluation of Iv acyclovir dosing and nephrotoxicity in critically ill Mulvey, Assessing the clinical impact of intravenous acyclovir dosing in

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Acyclovir may increase the nephrotoxic activities of Tenofovir disoproxil. Drink plenty of fluids. Dehydration with acyclovir predisposes patients to

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acyclovir and gentamicin both increase nephrotoxicity and/or ototoxicity. Use Caution/Monitor. ioversol. acyclovir and ioversol both increase nephrotoxicity and/or ototoxicity. Modify Therapy/Monitor Closely. mycophenolate. acyclovir will increase the level or effect of mycophenolate by acidic (anionic) drug competition for renal tubular clearance.

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The case described in this vignette is an example of the clinical manifestation of acyclovir crystal obstructive nephrotoxicity. We will briefly discuss the pathophysiology, diagnosis, prevention, and management of patients that present with acyclovir nephrotoxicity.

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For decades, acyclovir-induced nephrotoxicity was believed to be secondary to crystalluria. Clinical evidence of nephrotoxicity in the absence of crystalluria suggests that acyclovir induces direct insult to renal tubular cells. We postulated that acyclovir is metabolized by the alcohol dehydrogenas

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acyclovir is discontinued. It is likely that most cases of acyclovir nephrotoxicity, which is likely due in part to direct tubular toxicity

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Dosing Uses. AdultPediatric. ADULT. Dosage Forms Strengths. injectable solution acyclovir. acyclovir and amikacin both increase nephrotoxicity and/or

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