Rosuvastatin is an oral drug for lowering blood cholesterol levels. Rosuvastatin is used for the reduction of blood total cholesterol, HDL cholesterol, and triglyceride levels, and to increase HDL cholesterol levels.
However, low levels of HDL cholesterol have not been established as causative of this increase in risk. (See 'Low HDL cholesterol as an ASCVD risk factor' below and 'Effect of increasing HDL cholesterol on clinical outcome' below.) This topic will address clinical aspects of abnormal HDL (the particle) and HDL cholesterol.
decrease LDL (bad) cholesterol and triglyceride levels. increase HDL (good) cholesterol levels. decrease the Total Cholesterol/HDL-Cholesterol Ratio (TC: HDL-C
Increasing HDL levels ; HDL lipoprotein particles that bear apolipoprotein C3 ; Most saturated fats ; HDL levels can be increased by smoking cessation ; Cannabis
There are several basic mechanisms by which a drug can raise HDL cholesterol: an increase in the uptake of cholesterol from tissues by HDLs; an increase in the transfer of cholesterol from other lipoproteins to HDLs; a reduction of the rate of transfer of cholesteryl esters from HDLs to the liver; and a reduction of cholesteryl ester transfer
It seems counterintuitive that increasing good drug companies remain invested in identifying drugs to increase HDL cholesterol.
medication used to increase HDL has been proven to improve health. As of 2024, numerous lifestyle changes and drugs to increase HDL levels were under study.
Niacin has been promoted for decades as a high-density lipoprotein (HDL)-raising drug. increasing HDL-P. Niacin is an LDL-lowering drug, specifically
by MS Kostapanos 2024 Cited by 342,4,9 Therefore, the examination of the effect of various hypolipidemic drugs on the HDL The dose-dependent increase in HDL-cholesterol levels, in our study
Isaac Asimov’s Three Laws of Robots does not apply here. Lots of possibilities.
Howard Campbell could be named after John W. Campbell who shaped sci-fi for the readers’ enjoyment.
Shame on HDL for not providing a sequel for his readers. Not nice to leave them hanging.
The story has a single focus. Expand the scope with subplots which become plots.
HDL, rewrite, edit and polish your story and sequel.
That’s how Sci-Fi Grandmasters are thusly honored by their works.
Best of luck in your endeavors.