When allopurinol is prescribed in the treatment of leishmaniasis or for use in birds and reptiles, it is referred to as off-label use. Many drugs are
Similar to diagnosis, treatment of leishmaniasis can be quite challenging (Table (Table3). 3). Overall, leishmaniasis treatment should be tailored individually to the patient and the type of leishmaniasis, as well as to the parasite subspecies.
However, it has major limitations in the treatment of leishmaniasis because of its teratogenicity effects and the long lifespan, which could favor promoting drug resistance.19 Chemotherapy is the most practical and effective treatment applied to all three major forms of leishmaniasis.
Although leishmaniasis is an ancient disease, its treatment is still challenging. Several drugs, differing in their cost, toxicity, treatment duration and emergence of drug resistance, are used for different types of leishmaniasis. To overcome these limitations, the search for newer drugs and other treatments continues.
Indeed, limited number of registered drugs for leishmaniasis with the high costs of treatment, toxicity and drug resistance remain significant challenges for health authorities. This led to the concept of drug repurposing, where the clinically approved drugs used for treatment of other diseases can be used for leishmaniasis.
A number of drugs have been employed for the treatment of leishmaniasis. A brief account of the mechanism of action and mode of administration of these drugs
by R Sivayogana 2024 Cited by 5Amphotericin B [5] is the first-line drug for visceral leishmaniasis and the second choice of drug for mucocutaneous leishmaniasis. Can be used in leishmaniasis
Treatment for leishmaniasis miltefosine (Impavido) liposomal amphotericin B (AmBisome) sodium stibogluconate, a drug that contains antimony
Although leishmaniasis is an ancient disease, its treatment is still challenging. Several drugs, differing in their cost, toxicity, treatment duration and emergence of drug resistance, are used for different types of leishmaniasis. To overcome these limitations, the search for newer drugs and other treatments continues.
Comments
4*
Collin’s punishment would have been better if she got to witness it.
As for the gentle treatment? If nothing else then it’s stupid to beak the merchandise mentally or physically. There are plenty of sickos who delight in that kind of thing themselves.
1. My GP doctor explained that the drugs are only half of the treatment, and actually the 'crutch' half of the treatment -that (in my own words) without dealing with my mis-wired brain, the drugs would only ever be a bandaid holding my wound together.
2. If at first you don't succeed, try and try again! Try different KINDS of psychologists, psychiatrists, social workers etc.
I went to 6, yep, SIX different psychologists before I clicked with one finally. I was seeing her for a few years when a chance appointment with a social worker showed me that you didn't need a piece of paper in psychology to get the message across even better -in other words, this social worker clicked with me even more than the great psychologist!