Contraindications for levothyroxine

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Author: Admin | 2025-04-28

Levothyroxine oral tablet is a generic drug prescribed for hypothyroidism and thyroid cancer. It has interactions with some other drugs, certain supplements, and specific foods, including antacids, iron supplements, and coffee.Levothyroxine is prescribed for hypothyroidism (underactive thyroid) in adults and children of all ages. The drug is also prescribed to lower levels of thyroid-stimulating hormone in adults and children with a certain type of thyroid cancer.Levothyroxine oral tablet is available as the brand-name drugs Euthyrox, Synthroid, Levoxyl, and Unithroid.An interaction occurs when one substance causes another substance to have a different effect than expected.Levothyroxine also comes as an oral capsule, an oral solution, and an intravenous (IV) injection. The oral capsule has the same interactions as levothyroxine oral tablet. The IV injection has different interactions.This article will focus on interactions for the oral tablet form of levothyroxine. You can talk with your doctor to learn more about interactions for the other forms of levothyroxine.To learn more about levothyroxine’s interactions, keep reading. For additional information, including details about its uses, see this other article about levothyroxine.Before you start treatment with levothyroxine, tell your doctor and pharmacist which prescription, over-the-counter, and other medications you take. By sharing this information with them, you may help prevent possible interactions. (To learn whether levothyroxine interacts with supplements, herbs, or vitamins, see the “Levothyroxine and other interactions” section.)If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.Here’s a table of drugs that can interact with levothyroxine. Keep in mind that this table doesn’t include all drugs that may interact with levothyroxine. Some of these interactions are described in detail in “Drug interactions in depth.”In some cases, factors or conditions could prevent your doctor from prescribing levothyroxine due to the risk of harm. These are known as contraindications. The contraindications of levothyroxine include:Having untreated adrenal insufficiencyDoctors typically will not prescribe levothyroxine for people with untreated adrenal insufficiency. If you have this condition, your adrenal glands don’t make enough steroid hormones, such as cortisol.Levothyroxine can lower the levels of steroid hormones in your body, so it can worsen adrenal insufficiency and could potentially trigger an adrenal crisis. If you have adrenal insufficiency, your doctor will prescribe medication to correct your steroid hormone levels before you start taking levothyroxine.Note: Before you start treatment with levothyroxine, it’s important to tell your doctor if this contraindication applies to you. They can determine whether to prescribe levothyroxine.There are no known interactions between levothyroxine and alcohol.If you have questions about drinking alcohol while taking levothyroxine, talk with your doctor or pharmacist.Here’s a closer look at certain drug interactions of levothyroxine.AntacidsAntacids are medications used to reduce symptoms of indigestion and heartburn.Interaction result: Taking antacids with levothyroxine can make levothyroxine less effective.Interaction explained: When taken at the same time as levothyroxine, antacids can reduce your body’s ability to absorb (take up) levothyroxine. As a result, the level of levothyroxine in your body will be lower, which can make the drug less effective.Examples of antacid drugs: Here are some antacids

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