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Author: Admin | 2025-04-28
Even in men, hot flashes are possible. You think, “I’m a man, there’s no way I’m going to feel like I’m in menopause.” Prednisone can make you feel like you’re a menopausal woman and you can get hot flashes with the sweating, the redness, the flushing, and even the mood changes.Testosterone-Related Changes from PrednisoneBecause prednisone is structurally similar to testosterone, these next side effects are related to the level of the male hormone, testosterone, changing while on prednisone.Male HormonesVoiceSpermDysmotilityLower countSex DriveAcneVoice Changes from PrednisoneThe male hormones like testosterone can change things like your voice. So you might get a little huskier voice than usual. It might give you a higher voice than usual. It’s just unpredictable and rare, but it’s possible.Sperm & Fertility Changes from PrednisoneEither the sperm can have dysmotility, which means they can’t swim as well. They’re just not built to swim quite as well as they’re used to. Or the sperm might have a lower count. So it’s possible to have a little bit less fertility while on prednisone because essentially there’s not the right balance of hormones of the estrogen and the progesterone to the testosterone in the body to create the most fertile environment.Sex Drive While on PrednisoneMen in support groups have shared that they have less sex drive at high doses of prednisone. They report that as the dose of prednisone gets lower, their drive tends to recover as well.Acne from PrednisonePrednisone is well-known for causing many skin issues. One of those may be hormonally-related to the testosterone, being acne.Muscle Wasting from PrednisonePrednisone is NOT an anabolic steroid, which would build muscles. Instead, it causes muscles to waste away. While not necessarily a male-specific side effect, for some men, this can be disheartening.One man called to let me know that he was a competitive bodybuilder, and since taking prednisone, he’d lost so much muscle mass, he could no longer compete. I recommended he continue weight lifting (under his doctor’s supervision) and eat a diet rich in collagen and protein.Here are some collagen supplements I recommend.Psychiatric Side EffectsMen are less likely to have psychiatric side effects of prednisone.But when they do, men are more likely to have these psychiatric side effects:ManiaDelirium‘Roid RageMood changes and psychiatric side effects of prednisone are different in men and women. Men often have less overall psychiatric side effects than women. But when men do get psychiatric side effects, they can be more extreme.Men are more likely to become psychotic, to have mania, and feel totally unlike themselves. Another possibility is a kind of crazy delirium; to just be incoherent and babbling and not “with it” at all.Just not feel like your normal self. That is more typical in men than
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